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Table 2 Expression of afadin and clinicopathological characteristics in OS patients

From: CLDN2 inhibits the metastasis of osteosarcoma cells via down-regulating the afadin/ERK signaling pathway

Item

N

Afadin (high)

Afadin (low)

P

Tumor tissue

27

11

16

< 0.001*

Normal

10

8

2

 

Age (years)

 ≤ 19

15

6

9

0.341

 > 19

12

5

7

 

Gender

 Male

16

6

10

1.000

 Female

11

5

6

 

Stage

    

 IA–IIA

10

4

6

0.584

 IIB–III

17

7

10

 

Response to chemotherapy

 Poor

9

3

6

0.127

 Good

7

1

6

 

 NA (n = 8)

11

   

Pulmonary metastasis

 +

21

7

14

< 0.001*

 −

6

4

2

 
  1. NA not available
  2. * Statistical significance was found with the Chi-square test/Chi-square goodness-of-fit test
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Cancer Cell International

ISSN: 1475-2867

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