Fig. 3

Overexpression of SKA3 accelerates CC tumor growth in vivo. a Representative picture of xenograft tumors formed. b Growth curves of xenograft tumors derived from HeLa cells with stable SKA3 overexpression, SKA3 knockdown and control plasmid expression. c Representative images of IHC staining for SKA3 and Ki67 in tumor sections (magnifications ×200). Data (mean ± SD; n = 6) were analyzed by Student’s t test (*p < 0.05, **p < 0.01, over-SKA3 vs. control vector. ^#p < 0.05, ^##p < 0.01, SKA3 knockdown vs. control vector)