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Fig. 3 | Cancer Cell International

Fig. 3

From: HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells

Fig. 3

HOXC6 gene silencing inhibits the activation of the TGF-β1/smad signaling pathway in CC cells. a mRNA expression of HOXC6, TGF-β1, TGF-β RII, smad4 and smad7 in HeLa cells; b gray values of HOXC6, TGF-β1, TGF-β RII, smad4, smad7, and GAPDH in HeLa cells; c protein expression of HOXC6, TGF-β1, TGF-β RII, smad4 and smad7 in HeLa cells; d mRNA expression of HOXC6, TGF-β1, TGF-β RII, smad4 and smad7 in SiHa cells; e gray values of HOXC6, TGF-β1, TGF-β RII, smad4, smad7, and GAPDH in SiHa cells; f protein expression of HOXC6, TGF-β1, TGF-β RII, smad4 and smad7 in SiHa cells; *p < 0.05 compared with the blank group; #p < 0.05, compared with the NC group; &p < 0.05, compared with the SB431542 group. NC negative control, GAPDH glyceraldehyde-3-phosphate dehydrogenase, HOXC6 homeobox C6, TGF-β transforming growth factor-β, smad solvated metal atom dispersion, RT-qPCR reverse transcription quantitative polymerase chain reaction

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