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Table 2 Stratification analyses the association between polymorphisms in TGF-BR1 and gastric cancer risk

From: Polymorphisms of TGFBR1, TLR4 are associated with prognosis of gastric cancer in a Chinese population

Genotype Age Gender H. pylori infection
≤ 64 > 64 Male Female Positive Negative
Ca/Co OR (95% CI)a p value Ca/Co OR (95% CI)a p value Ca/Co OR (95% CI)a p value Ca/Co OR (95% CI)a p value Ca/Co OR (95% CI)a p value Ca/Co OR (95% CI)a p value
rs6478974
 TT 100/87 Reference   119/107 Reference   156/134 Reference   63/60 Reference   120/91 Reference   99/103 Reference  
 AT 101/113 0.76 (0.51,1.13) 0.175 103/107 0.85 (0.58,1.25) 0.412 159/170 0.80 (0.58,1.10) 0.164 45/50 0.81 (0.46,.41) 0.452 108/107 0.76 (0.52,1.12) 0.160 96/113 0.86 (0.58,1.28) 0.457
 AA 28/30 0.76 (0.41,1.40) 0.374 28/39 0.61 (0.34,1.07) 0.082 38/54 0.55 (0.33,0.90) 0.017 18/15 1.19 (0.55,2.58) 0.663 33/33 0.73 (0.41,1.28) 0.272 23/36 0.62 (0.34,1.14) 0.127
 AT/AA 129/143 0.76 (0.52,1.11) 0.156 131/146 0.80 (0.56,1.14) 0.206 197/224 0.74 (0.54,1.00) 0.049 63/65 0.89 (0.54,1.48) 0.658 141/140 0.75 (0.52,1.08) 0.125 119/149 0.81 (0.55,1.17) 0.260
 Additive model   0.83 (0.63,1.10) 0.199   0.81 (0.62,1.04) 0.100   0.76 (0.61,0.95) 0.016   1.01 (0.70,1.44) 0.975   0.83 (0.64,1.08) 0.157   0.81 (0.62,1.07) 0.135
rs334348
 AA 72/74 Reference   71/84 Reference   108/121 Reference   35/37 Reference   77/83 Reference   66/75 Reference  
 AG 105/122 0.95 (0.62,1.47) 0.832 116/118 1.16 (0.77,1.76) 0.478 168/173 1.15 (0.81,1.62) 0.143 53/67 0.85 (0.46,1.54) 0.583 124/100 1.43 (0.94,2.17) 0.093 97/140 0.79 (0.51,1.21) 0.278
 GG 52/34 1.57 (0.90,2.73) 0.114 63/51 1.44 (0.88,2.37) 0.146 77/64 1.37 (0.89,2.11) 0.149 38/21 1.97 (0.94,4.11) 0.072 60/48 0.37 (0.83,2.25) 0.223 55/37 1.71 (0.99,2.53) 0.054
 AG/GG 157/156 1.09 (0.72,1.63) 0.694 179/169 1.26 (0.86,1.85) 0.245 245/237 1.20 (0.87,1.66) 0.269 91/88 1.10 (0.63,1.92) 0.745 184/148 1.40 (0.95,2.06) 0.088 152/177 0.98 (0.66,1.47) 0.927
 Additive model   1.21 (0.93,1.59) 0.161   1.22 (0.95,1.56) 0.113   1.17 (0.95,1.45) 0.141   1.36 (0.95,1.94) 0.096   1.19 (0.93,1.53) 0.166   1.25 (0.96,1.64) 0.097
rs10512263
 TT 130/129 Reference   149/133 Reference   202/189 Reference   77/73 Reference   150/127 Reference   129/135 Reference  
 CT 88/88 0.95 (0.64,1.41) 0.814 90/99 0.80 (0.55,1.16) 0.230 136/140 0.89 (0.65,1.22) 0.470 42/47 0.82 (0.48,1.41) 0.471 98/87 0.91 (0.62,1.33) 0.610 80/100 0.83 (0.56,1.22) 0.335
 CC 11/13 0.70 (0.29,1.67) 0.417 11/21 0.44 (0.20,0.96) 0.040 15/29 0.41 (0.21,0.81) 0.010 7/5 1.40 (0.42,4.63) 0.585 13/17 0.64 (0.29,1.39) 0.258 9/17 0.45 (0.19,1.10) 0.080
 CT/CC 99/101 0.91 (0.62,1.33) 0.621 101/120 0.74 (0.52,1.06) 0.101 151/169 0.80 (0.59,1.09) 0.159 49/52 0.87 (0.52,1.46) 0.604 111/104 0.86 (0.60,1.23) 0.405 89/117 0.77 (0.53,1.13) 0.180
 Additive model   0.88 (0.64,1.21) 0.441   0.74 (0.55,0.99) 0.040   0.76 (0.60,0.98) 0.033   0.96 (0.63,1.48) 0.864   0.85 (0.63,1.14) 0.272   0.76 (0.56,1.04) 0.083
  1. Italic represents any values with p < 0.05
  2. OR odds ratio, Ca case, Co control
  3. aAdjusted for age, gender, smoking, drinking, and H. pylori infection status