Table 4 Association between polymorphism and overall survival of gastric cancer patients in co-dominant model
Genotype | Cases, n | Death, n (%) | Log-rank p-value | HR | HR (95% CI)a | p-value |
|---|---|---|---|---|---|---|
rs4072111 | ||||||
CC | 322 | 205 (0.64) | Reference | Reference | ||
TC/TT | 138 | 81 (0.59) | 0.344 | 0.88 (0.68,1.14) | 1.12 (0.86,1.45) | 0.408 |
rs4778889 | ||||||
TT | 256 | 172 (0.67) | Reference | Reference | ||
CT/CC | 204 | 114 (0.56) | 0.028 | 0.77 (0.61,0.97) | 0.84 (0.66,1.06) | 0.146 |
rs11556218 | ||||||
TT | 293 | 192 (0.66) | Reference | Reference | ||
GT/GG | 167 | 94 (0.56) | 0.110 | 0.82 (0.64,1.05) | 0.94 (0.73,1.20) | 0.607 |
rs859 | ||||||
AA | 109 | 68 (0.62) | Reference | Reference | ||
GA/GG | 351 | 218 (0.62) | 0.633 | 1.07 (0.81,1.40) | 1.03 (0.79,1.36) | 0.814 |
rs1131445 | ||||||
TT | 211 | 127 (0.60) | Reference | Reference | ||
CT/CC | 249 | 159 (0.64) | 0.150 | 1.18 (0.94,1.50) | 1.06 (0.84,1.35) | 0.617 |
rs10759932 | ||||||
TT | 231 | 141 (0.61) | Reference | Reference | ||
TC/CC | 229 | 145 (0.63) | 0.563 | 1.07 (0.85,1.35) | 1.07 (0.84,1.35) | 0.588 |
rs1927911 | ||||||
GG | 165 | 95 (0.58) | Reference | Reference | ||
GA/AA | 295 | 191 (0.65) | 0.113 | 1.22 (0.95,1.56) | 1.27 (1.00,1.63) | 0.054 |
rs11536889 | ||||||
GG | 293 | 181 (0.62) | Reference | Reference | ||
CG/CC | 167 | 105 (0.63) | 0.957 | 1.01 (0.79,1.28) | 0.99 (0.77,1.26) | 0.924 |
rs6478974 | ||||||
TT | 212 | 126 (0.59) | Reference | Reference | ||
TA/AA | 248 | 160 (0.65) | 0.224 | 1.16 (0.92,1.46) | 1.23 (0.98,1.56) | 0.079 |
rs334348 | ||||||
GG | 110 | 64 (0.58) | Reference | Reference | ||
AG/AA | 350 | 222 (0.63) | 0.491 | 1.10 (0.84,1.46) | 1.04 (0.79,1.38) | 0.787 |
rs10512263 | ||||||
TT | 269 | 157 (0.58) | Reference | Reference | ||
CT/CC | 191 | 129 (0.68) | 0.031 | 1.29 (1.02,1.63) | 1.29 (1.02,1.63) | 0.031 |