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Table 5 Subgroup analyses of association between polymorphisms and survival in co-dominant model

From: Polymorphisms of TGFBR1, TLR4 are associated with prognosis of gastric cancer in a Chinese population

Group

Case, n

Death, n (%)

rs1927911

rs10512263

GA/AA: GG

HR (95% CI)a

p-value

CT/CC: TT

HR (95% CI)a

P-value

Age

 < 64

224

130 (0.58)

142/82

1.64 (1.13,2.38)

0.009

97/127

1.34 (0.95,1.90)

0.099

 ≥ 64

236

156 (0.66)

153/83

1.04 (0.75,1.45)

0.817

94/142

1.19 (0.86,1.64)

0.286

Gender

 Male

338

214 (0.63)

216/122

1.36 (1.03,1.81)

0.033

145/193

1.43 (1.09,1.87)

0.010

 Female

122

72 (0.64)

79/43

1.08 (0.65,1.80)

0.754

46/76

1.26 (0.76,2.08)

0.365

Clinical stage

 T1–T2

159

42 (0.26)

102/57

1.36 (0.70,2.66)

0.367

60/99

2.61 (1.40,4.86)

0.003

 T3–T4

301

244 (0.81)

193/108

1.21 (0.93,1.58)

0.160

131/170

1.04 (0.80,1.34)

0.784

Tumor site

 Cardiac

132

87 (0.66)

91/41

1.07 (0.67,1.71)

0.768

54/78

1.47 (0.94,2.31)

0.094

 Non-cardiac

328

199 (0.61)

204/124

1.34 (1.00,1.80)

0.050

137/191

1.36 (1.02,1.80)

0.034

  1. Italic represents any values with p < 0.05
  2. aAdjusted for age, sex, tumor site and TNM stage