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Table 1 Characteristics of glioma patients in low and high ADAR3 expression group in CGGA dataset

From: ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

Variable Total (n = 309) High ADAR3 expression (n = 154) Low ADAR3 expression (n = 155) P value
Age
 < 45 178 104 74 0.0005
 ≥ 45 131 50 81  
Gender
 Male 115 57 58 1
 Female 194 97 97  
Grade
 II 104 86 18 < 0.0001
 III 67 35 32  
 IV 138 33 105  
KPS
 < 80 58 42 16 0.0006
 ≥ 80 108 46 62  
 NA 143 67 76  
Subtype
 Neural 76 71 5 < 0.0001
 Proneural 99 61 38  
 Classical 69 14 55  
 Mesenchymal 65 8 57  
IDH mutation
 Mutant 155 108 47 < 0.0001
 Wildtype 154 46 108  
MGMT
 Unmethylated 111 48 63 0.0462
 Methylated 136 67 69  
 NA 62 39 23  
1p/19q deletion
 No 220 102 118 < 0.0001
 Yes 36 31 5  
 NA 53 21 32  
TERT
 No 158 79 79 0.6426
 Yes 91 43 48  
 NA 60 33 27