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Fig. 4 | Cancer Cell International

Fig. 4

From: miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

Fig. 4

miR-133b and FGFR1 critically controlled the migration and the invasion of OS cells. a, b The migration of MG-63 and U2OS cells transfected with miR-133b mimics vs. miR-133b NC, or with shFGFR1 vs. shNC was examined by wound healing assay, with representative images shown in a and % of wound closure quantified and averaged from three independent experiments shown in b. c, d The representative images of migrated and invaded MG-63 and U2OS cells transfected with miR-133b mimics vs. miR-133b NC, or with shFGFR1 vs. shNC were examined by Transwell migration and invasion assay, respectively. **P < 0.01 and ***P < 0.001

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