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Table 1 Associations between miR-133b/FGFR1 expression and clinicopathological characteristics in patients with osteosarcoma

From: miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

Clinical parameters

Cases (n)

Expression level

P value

Expression level

P value

miR-133bhigh

miR-133blow

(*P < 0.05)

FGFR1high

FGFR1low

(*P < 0.05)

Age (years)

 < 18 years

20

13

7

0.0502

8

12

0.0577

 ≥ 18 years

10

2

8

 

8

2

 

Gender

 Male

15

1

14

< 0.0001

10

5

0.2723

 Female

15

14

1

 

6

9

 

Tumor size (cm)

 < 5

12

8

4

0.2635

5

7

0.4572

 ≥ 5

18

7

11

 

11

7

 

Location

 Femur/Tibia

22

14

8

0.0352

9

13

0.0395

 Elsewhere

8

1

7

 

7

1

 

TNM stage

 I

14

12

2

0.0007

4

10

0.0261

 II + III

16

3

13

 

12

4

 

Distant metastasis

 Yes

16

4

12

0.0092

13

3

0.0027

 No

14

11

3

 

3

11

 
  1. * P < 0.05 was considered significantly different