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Table 1 Associations between miR-133b/FGFR1 expression and clinicopathological characteristics in patients with osteosarcoma

From: miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

Clinical parameters Cases (n) Expression level P value Expression level P value
miR-133bhigh miR-133blow (*P < 0.05) FGFR1high FGFR1low (*P < 0.05)
Age (years)
 < 18 years 20 13 7 0.0502 8 12 0.0577
 ≥ 18 years 10 2 8   8 2  
Gender
 Male 15 1 14 < 0.0001 10 5 0.2723
 Female 15 14 1   6 9  
Tumor size (cm)
 < 5 12 8 4 0.2635 5 7 0.4572
 ≥ 5 18 7 11   11 7  
Location
 Femur/Tibia 22 14 8 0.0352 9 13 0.0395
 Elsewhere 8 1 7   7 1  
TNM stage
 I 14 12 2 0.0007 4 10 0.0261
 II + III 16 3 13   12 4  
Distant metastasis
 Yes 16 4 12 0.0092 13 3 0.0027
 No 14 11 3   3 11  
  1. * P < 0.05 was considered significantly different