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Fig. 1 | Cancer Cell International

Fig. 1

From: Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3

Fig. 1

Bioinformatics analysis of TRIP13. a The visual hierarchical cluster analysis was performed using Volcano plot in HCC. b The visual hierarchical cluster analysis was performed using Heat map in HCC. c The cases of 50 normal liver tissues and 374 HCC tumor tissues were downloaded from TCGA. 1163 of cross differential genes were obtained from edgeR, WilcoxTest and survival analysis via Venn diagram. d The expression of TRIP13 with overall survival was analyzed by Kaplan–Meier curve. P = 2.885e−06. The biology significance was performed by GSEA on KEGG pathways. TRIP13 was mainly increased in RNA degradation (e) and fatty acid metabolism (f). g Transcriptional expression analysis of TRIP13 was shown by cBioPortal in HCC. mRNA analysis for HCC were available on cBioPortal with 371 samples. Survival analysis by TRIP13 mRNA expression was shown on cBioPortal in HCC. The overall survival (h) and the disease-free survival (i) were shown in months in the Kaplan–Meier analysis

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Cancer Cell International

ISSN: 1475-2867

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