Fig. 4
High molecular weight kininogen (HMWK) content changes after NP treatment in human metastatic breast cancer cells supernatant. Cell culture supernatant content was analyzed by enzyme immune-assay. a, b HMWK content does not changed at 15 or 30 min and increased at 60 min (c) after NP treatment, in MDA-MB-231LUC+ cells supernatant. Three to five independent experiments were performed. Data are presented as median (numbers and horizontal line) with boxes representing the 25 and 75 percentiles, *P < 0.05; **P < 0.01; ***P < 0.001 compared to control