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Fig. 3 | Cancer Cell International

Fig. 3

From: Speckle-type POZ protein functions as a tumor suppressor in non-small cell lung cancer due to DNA methylation

Fig. 3

SPOP expression is induced by AZA treatment in methylated lung cancer cells. a DNA methylation status of the SPOP gene proximal promoter was analyzed by bisulfite sequencing in AZA-treated cells. b SPOP mRNA and protein levels were determined by qPCR and western blotting in the indicated cells treated with varying concentrations of AZA. c Effect of AZA on lung cancer cell growth. MTT assay was used to detect the growth of cell treated with different concentrations of AZA. The data are presented as the mean ± SD of three independent experiments. *P < 0.05 as compared with control (Non-treated with AZA)

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Cancer Cell International

ISSN: 1475-2867

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