Table 1 Clinicopathological characteristics and SPOP methylation in 82 NSCLC patients
Clinicopathological characteristics | Number (n = 82) | SPOP methylation | P | ||
|---|---|---|---|---|---|
Methylated (n = 33) | Partial methylation (n = 28) | Unmethylated (n = 21) | |||
Age (years) | 0.448 | ||||
≤ 60 | 44 | 15 | 16 | 13 | |
> 60 | 38 | 18 | 12 | 8 | |
Gender | 0.416 | ||||
Male | 48 | 22 | 14 | 12 | |
Female | 34 | 11 | 14 | 9 | |
Histologic type | 0.086 | ||||
Adenocarcinoma | 63 | 29 | 21 | 13 | |
Squamous cell carcinoma | 19 | 4 | 7 | 8 | |
Smoking status | 0.064 | ||||
Ever | 34 | 9 | 16 | 9 | |
Never | 48 | 24 | 12 | 12 | |
Staging | 0.903 | ||||
I + II | 60 | 25 | 20 | 15 | |
III + IV | 22 | 8 | 8 | 6 | |
Pathology grade | 0.018* | ||||
Well | 14 | 3 | 2 | 9 | |
Moderate | 43 | 20 | 15 | 8 | |
Poor | 25 | 10 | 11 | 4 | |
Lymph node metastasis | 0.094 | ||||
No | 45 | 23 | 13 | 9 | |
Yes | 37 | 10 | 15 | 12 | |