Fig. 8

Proteins involved in EMT and STAT3 pathway were determined by western-blot analysis with the use of inhibitor. DLD1-HOXB8 treated with p-STAT3 inhibitor after 12 h, DLD1-GFP without any treatment stands for a control. P-STAT3 inhibitor increased the expression of E-cadherin, and decreased the expression of Vimentin, N-cadherin, Twist, Zeb1 and Zeb2