Fig. 6

MiR-144 overexpression suppresses the tumor formation of SMMC-7721 cells in nude mice. a, b Photographs of nude mice and tumor tissues from different groups at day 30. c Growth curves of tumor volumes in xenografts of nude mice were determined based on tumor volume measured every 5 days for 30 days (n = 4). d Tumor weights of different groups at day 30 (n = 4). Data in a–d are representative of two independent experiments. *p < 0.05, **p < 0.01 vs. Lenti-Scramble, **p < 0.01 vs. Lenti-Scramble. e Representative immunohistochemistry images of Ki67 staining of tumor sections obtained from the Lenti-Scramble and Lenti-miR-144 mouse groups. Magnification ×200, scale bar = 10 μm