Table 2 Impact of drug treatment on AURKA and HPRT expression
Description | PTEZ score range | # samples | |
|---|---|---|---|
AURKA | Severe reduction | − 10 → − 6 | 78 |
Intermediate reduction | − 6 → − 2 | 396 | |
No effect | − 2 → 2 | 14,174 | |
Intermediate elevation | 2 → 6 | 141 | |
Severe elevation | 6 → 10 | 14 | |
HPRT1 | Severe reduction | − 10 → − 6 | 13 |
Intermediate reduction | − 6 → − 2 | 233 | |
No effect | − 2 → 2 | 14,553 | |
Intermediate elevation | 2 → 6 | 15 | |
Severe elevation | 6 → 10 | 0 |