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Table 2 mRNA expression of EMT and CSC markers in 7 days old HNSCC tumor spheroids relative to cells cultured in 2D

From: The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer

Gene

LK1108

LK0917

LK0858B

LK1122

LK0902

NANOG

11.1

1.9

4.7

26.8

11.3

SOX2

11.7

1.4

13.3

22.9

20.8

CD44

1.0

1.1

1.5

1.0

0.6

CDH1

1.5

1.4

2.8

1.6

8.8

CDH2

0.1

0.6

0.1

5.8

0.1

FN1

0.1

0.8

0.2

1.0

2.0

FOXC2

0.1

0.8

1.5

3.9

0.1

TWIST

0.8

1.4

5.9

0.9

2.1

VIM

0.1

0.4

0.1

1.0

0.2

  1. Upregulated genes—italics, downregulated genes—bold italics; each value represents the mean of two independent experiments