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Table 2 mRNA expression of EMT and CSC markers in 7 days old HNSCC tumor spheroids relative to cells cultured in 2D

From: The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer

Gene LK1108 LK0917 LK0858B LK1122 LK0902
NANOG 11.1 1.9 4.7 26.8 11.3
SOX2 11.7 1.4 13.3 22.9 20.8
CD44 1.0 1.1 1.5 1.0 0.6
CDH1 1.5 1.4 2.8 1.6 8.8
CDH2 0.1 0.6 0.1 5.8 0.1
FN1 0.1 0.8 0.2 1.0 2.0
FOXC2 0.1 0.8 1.5 3.9 0.1
TWIST 0.8 1.4 5.9 0.9 2.1
VIM 0.1 0.4 0.1 1.0 0.2
  1. Upregulated genes—italics, downregulated genes—bold italics; each value represents the mean of two independent experiments