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Fig. 7 | Cancer Cell International

Fig. 7

From: Long noncoding RNA PXN-AS1-L promotes non-small cell lung cancer progression via regulating PXN

Fig. 7

PXN knockdown attenuated the oncogenic roles of PXN-AS1-L in NSCLC. a The expressions of PXN in PXN-AS1-L stably overexpressed and control A549 cells after transient transfection of PXN specific shRNA were detected by qPCR. b Cell viability of PXN-AS1-L stably overexpressed and control A549 cells after transient transfection of PXN specific shRNA was detected by Glo cell viability assays. c Cell proliferation of PXN-AS1-L stably overexpressed and control A549 cells after transient transfection of PXN specific shRNA was detected by EdU incorporation assays. The red color indicates EdU-positive cells. Scale bars = 200 μm. d Cell apoptosis of PXN-AS1-L stably overexpressed and control A549 cells after transient transfection of PXN specific shRNA was detected by TUNEL assays. e Cell migration of PXN-AS1-L stably overexpressed and control A549 cells after transient transfection of PXN specific shRNA was detected by transwell assays. Scale bars = 100 μm. Results are shown as mean ± SD of three independent experiments. *P < 0.05, **P < 0.01 by Student’s t-test

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