Table 2 Univariate and multivariate analysis of overall survival using the Cox proportional hazard regression model

Age

< 60

1.18 (0.83–1.68)

≥ 60

Sex

Male

1.18 (0.82–1.69)

Female

Race

Asian

0.75 (0.52–1.09)

White + others

BMI

≤25

0.74 (0.51–1.06)

>25

Grade

1–2

1.14 (0.78–1.67)

3–4

TNM stage

I–II

2.48 (1.71–3.62)

2.02 (1.37–2.96)

III–IV

Wnt1

Decreased (0–0.87)

0.50 (0.35–0.72)

0.58 (0.39–0.85)

Increased (> 0.87)

Wnt2

Decreased (0–1.62)

1.42 (1.00–2.00)

Increased (> 1.66)

Wnt2B

Decreased (0–4.12)

1.29 (0.91–1.82)

Increased (> 4.12)

Wnt3

Decreased (2.58–37.97)

0.64 (0.45–0.91)

0.65 (0.45–0.96)

Increased (> 37.97)

Wnt3A

Decreased (0–3.51)

1.32 (0.91–1.90)

Increased (> 3.51)

Wnt4

Decreased (0–8.11)

1.49 (0.97–2.30)

Increased (> 8.11)

Wnt5A

Decreased (0–416.79)

1.38 (0.87–2.16)

Increased (> 416.79)

Wnt5B

Decreased (0.99–15.15)

0.51 (0.32–0.79)

0.56 (0.34–0.93)

Increased (> 15.15)

Wnt6

Decreased (0–9.01)

1.61 (1.08–2.41)

1.62 (1.05–2.51)

Increased (> 9.01)

Wnt7A

Decreased (0–0.24)

1.28 (0.90–1.82)

Increased (> 0.24)

Wnt7B

Decreased (0–4.01)

1.42 (0.99–2.02)

Increased (> 4.01)

Wnt8A

Decreased (0)

4.14 (1.51–11.3)

4.14 (1.47–11.68)

Increased (> 0)

Wnt8B

Decreased (0–2.17)

1.35 (0.84–2.15)

Increased (> 2.17)

Wnt9A

Decreased (0–0.24)

1.34 (0.95–1.90)

Increased (> 0.24)

Wnt9B

Decreased (0–2.19)

0.78 (0.52–1.16)

Increased (> 2.19)

Wnt10A

Decreased (0–4.38)

0.99 (0.99–1.01)

Increased (4.38–173.47)

Wnt10B

Decreased (0–6.16)

0.70 (0.47–1.03)

Increased (> 6.16)

Wnt11

Decreased (0–28.88)

0.70 (0.49–0.99)

Increased (> 28.88)

Wnt16

Decreased (0–1.62)

1.43 (0.97–2.13)

Increased (> 1.66)