A DAAM1 3′-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis

Table 2 Clinicopathological characteristics, allelic, and genotypes distribution in breast cancer patients

Characteristics	n	rs79036859^a		OR (95% Cl)	P value^b
Characteristics	n	AA	AG/GG	OR (95% Cl)	P value^b
Tumor size (cm)
≤ 2	61	37	24	1.20 (0.61–2.33)	0.599
> 2	87	49	38	1.20 (0.61–2.33)	0.599
Unknown	9
Lymph node metastasis
N0	121	70	41	3.90 (1.77–8.59)	< 0.001
N1–N3	36	12	24	3.90 (1.77–8.59)	< 0.001
Distant metastasis
M0	151	90	61	2.95 (0.52–16.62)	0.200
M1	6	2	4	2.95 (0.52–16.62)	0.200
ER status
Negative	51	29	22	0.90 (0.46–1.77)	0.759
Positive	106	63	43	0.90 (0.46–1.77)	0.759
PR status
Negative	67	38	29	0.85 (0.45–1.62)	0.619
Positive	89	54	35	0.85 (0.45–1.62)	0.619
Unknown	1
Her-2 status
Negative	94	51	43	0.67 (0.35–1.30)	0.233
Positive	61	39	22	0.67 (0.35–1.30)	0.233
Unknown	2
P53 status
Negative	105	63	42	1.30 (0.63–2.68)	0.485
Positive	41	22	19	1.30 (0.63–2.68)	0.485
Unknown	11
Ki67 status
Negative	33	22	11	1.55 (0.69–3.49)	0.285
Positive	119	67	52	1.55 (0.69–3.49)	0.285
Unknown	5

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