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Table 4 KEGG pathway analysis of aberrantly methylated-differentially expressed genes in PCa

From: Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

Category

Pathway

P-value

Hypermethylation-low expression

NOD-like receptor signaling pathway

7.37E−04

Pentose phosphate pathway

3.64E−03

Viral carcinogenesis

3.76E−03

Tryptophan metabolism

6.84E−03

Measles

8.68E−03

Hepatitis B

1.05E−02

Legionellosis

1.26E−02

Cytosolic DNA-sensing pathway

1.69E−02

Influenza A

1.71E−02

Inflammatory bowel disease (IBD)

1.74E−02

Hypomethylation-high expression

Pathways in cancer

1.47E−04

MAPK signaling pathway

1.67E−04

Wnt signaling pathway

2.01E−04

Colorectal cancer

2.78E−04

Pancreatic cancer

3.35E−04

Melanoma

4.15E−04

AGE-RAGE signaling pathway in diabetic complications

1.16E−03

Insulin resistance

1.44E−03

FoxO signaling pathway

2.55E−03

Hepatitis B

3.32E−03