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Table 5 GO terms analysis of hub genes in PCa

From: Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

Category

Term

P-value

Hypermethylation-low expression

Negative regulation of myeloid cell apoptotic process

1.05E−03

Positive regulation of tumor necrosis factor-mediated signaling pathway

1.20E−03

Regulation of macrophage apoptotic process

1.05E−03

Regulation of myd88-independent toll-like receptor signaling pathway

1.35E−03

Protein autoprocessing

1.50E−03

Establishment of viral latency

1.50E−03

Interleukin-23-mediated signaling pathway

1.50E−03

Cellular response to interferon-gamma

1.01E−04

Interleukin-21-mediated signaling pathway

1.35E−03

Regulation of myeloid leukocyte differentiation

1.65E−03

Hypomethylation-high expression

Telencephalon cell migration

1.05E−03

Regulation of endothelial cell chemotaxis to fibroblast growth factor

1.20E−03

Positive regulation of vascular endothelial cell proliferation

1.50E−03

Response to UV-A

1.05E−03

Cerebral cortex cell migration

1.05E−03

Regulation of collateral sprouting

1.20E−03

Neuron migration

1.23E−05

Positive regulation of protein serine/threonine kinase activity

1.05E−04

Mitotic G1 DNA damage checkpoint

1.65E−03

Regulation of cardiac muscle cell action potential involved in regulation of contraction

1.35E−03