Fig. 6
From: FOXD3 may be a new cellular target biomarker as a hypermethylation gene in human ovarian cancer
FOXD3 hypermethylation suppresses ovarian cancer apoptosis in vitro. a, b, c, f Flow cytometry showed that the percentage of cell apoptosis elevated in control group, but FOXD3 over-expression group and 5-Aza- dC group increased the most. The data from flow cytometry confirmed the results, *p < 0.05. d, e, g, h Expression levels of apoptotic proteins Annexin V, cleaved PARP and caspase-3 in SKOV3 and OV90 cells. The results showed that the expression level of apoptotic proteins in the over-expression FOXD3 group and the demethylated group was higher than that in the control group, **p < 0.01