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Fig. 7 | Cancer Cell International

Fig. 7

From: Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway

Fig. 7

Effects of EGCG on the EGFR/RAS/RAF/MEK/ERK signaling pathway in human thyroid carcinoma cells. a Western blotting analysis of the expression levels of p-EGFR, EGFR, RAS, p-RAF, RAF, p-MEK1/2, MEK1/2, p-ERK1/2, and ERK1/2 in TT, TPC-1, and ARO cells. β-actin was used as the loading control. b–f The intensities of the bands were quantified by densitometry analyses and normalized by the amount of EGFR, β-actin, RAF, MEK1/2, and ERK1/2, respectively. Data are presented as mean ± SEM of three independent experiments. *P < 0.05, **P < 0.01 compared with the control group

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