Table 5 Validation of the hub genes in TCGA
Category | Hub gene | Expression status | P value | Methylation status | P value |
|---|---|---|---|---|---|
Hypomethylated with high expression | AKT1 | Upregulated | 0.0063 | Hypomethylated | 7.17E−07 |
PRDM10 | Upregulated | 0.0031 | Hypomethylated | 4.62E−10 | |
CCND1 | – | – | Hypomethylated | 5.98E−19 | |
FASN | Upregulated | 3.85E−15 | Hypomethylated | 6.36E−21 | |
Hypermethylated with low expression | FLNA | Downregulated | 2.05E−29 | Hypermethylated | 6.99E−20 |
PRKCB | Downregulated | 3.54E−37 | – | – |