Fig. 1

HNF4α expression is increased in PDAC tissues. a Representative images of IHC staining for HNF4α in PDAC and adjacent normal tissues (scale bar, 50 μm). b HNF4α expression in PDAC and adjacent normal tissues, as determined by the IHC score (n = 30, ****P < 0.0001). c Representative images of IHC staining for HNF4α in tissue microarrays (scale bar, 200 µm; inset scale bar, 50 µm). d The overall survival of patients with PDAC was analyzed using the Kaplan–Meier analysis on the basis of HNF4α expression (n = 105, *P = 0.0281). e Western blotting analysis of HNF4α expression in PDAC cell lines; β-actin was used as a control