Table 3 Univariate and multivariate Cox regression of overall survival for patients with PDAC
Characteristics | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age (years) | ||||||
 > 60 | 1.195 | 0.788 to 1.812 | 0.402 |  | – |  |
 ≤ 60 | ||||||
Gender | ||||||
 Male | 0.842 | 0.550 to 1.290 | 0.430 |  | – |  |
 Female | ||||||
TNM stage | ||||||
 IIb, III, IV | 1.722 | 1.133 to 2.619 | 0.011* |  | – |  |
 I, IIa | ||||||
Tumor size (cm) | ||||||
 ≥ 4.0 | 1.809 | 1.148 to 2.851 | 0.011* | 1.919 | 1.210 to 3.041 | 0.006** |
 < 4.0 | ||||||
Histological grade | ||||||
 Grade 3 | 1.200 | 0.782 to 1.841 | 0.403 |  | – |  |
 Grade 1,2 | ||||||
Lymph node status | ||||||
 Positive | 1.826 | 1.201 to 2.778 | 0.005** | 1.887 | 1.237 to 1.049 | 0.003** |
 Negative | ||||||
Vascular emboli | ||||||
 Positive | 1.012 | 0.571 to 1.791 | 0.968 |  | – |  |
 Negative | ||||||
HNF4α expression | ||||||
 High | 1.560 | 1.012 to 2.404 | 0.044* | 1.616 | 1.049 to 2.491 | 0.030* |
 Low | ||||||