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Fig. 4 | Cancer Cell International

Fig. 4

From: WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia

Fig. 4

USP24 is upregulated and has negative correlation with the overall survival in T-ALL/TCL patients. a Analysis of TCGA leukemia dataset from the Oncomine database to assess the expression of USP24 in normal peripheral blood cells and in T-ALL patient samples. The data are presented with box plots. Fold change, P-value (determined by Student’s t-test), and sample size are shown. b, c The prognostic value of USP24 and USP9X expression at the mRNA level was verified according to the data of R2 microarray database (https://hgserver1.amc.nl/cgi-bin/r2/main.cgi), and this results indicated that the lower expression of USP24 but higher expression of USP9X at the mRNA level was significantly associated with a better survival of the T-ALL/TCL patients (P < 0.05)

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