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Table 3 Nucleotide sequence variations in the LCR of HPV16 (n = 95)

From: Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China

 

n = 95

LCR base sites

HPV16:

T

A

A

C

A

A

C

A

C

T

A

T

T

G

T

7

7

7

7

7

7

7

7

7

7

7

7

7

7

7

1

2

2

2

2

2

3

3

3

4

4

4

4

6

7

Variants:

9

3

5

6

8

8

0

2

9

0

1

3

4

9

1

9

1

3

8

5

7

8

3

3

4

7

8

7

9

1

C

C

G

T

C

C

T

C

T

G

G

G

C

A

G

E reference:

T

A

A

C

A

A

C

A

C

T

A

T

T

G

T

AA:

T

C

A

C

A

A

C

A

T

T

A

T

T

G

T

As:

C

C

A

T

C

C

C

A

C

T

A

T

T

G

T

Af:

T

A

A

C

A

A

C

A

C

T

A

T

T

G

T

Mutation:

16

2

1

16

16

11

1

1

1

1

9

1

39

3

16

Ep-350T

16

               

Ep-350T

2

               

Ep

2

               

Ep

1

               

Ep

1

C

              

Ep

1

C

     

T

 

T

      

Ep

1

               

E-T7711G

15

              

G

E-T7711G

1

         

G

    

G

E-T7447C

27

            

C

  

E-T7447C

7

            

C

  

E-T7447C

3

            

C

A

 

E-T7447C

1

            

C

  

E-T7447C

1

            

C

  

As

9

C

  

T

C

C

    

G

    

As

2

C

  

T

C

          

As

2

C

  

T

C

          

As

1

C

  

T

C

C

 

C

       

As

1

C

 

G

T

C

C

         

As

1

C

  

T

C

      

G

   
 

n = 95

LCR base sites

 

HPV16:

A

T

G

G

T

G

C

G

G

A

     

7

7

7

7

7

7

7

7

7

7

C

C

A

C

 

7

7

7

8

8

8

8

8

8

8

1

2

4

7

 

Variants:

2

7

9

0

2

3

3

3

6

7

3

4

1

3

 

7

8

6

3

4

1

7

9

6

1

T

T

C

T

 

C

C

A

A

C

C

T

A

A

G

     

E reference:

A

T

G

G

T

G

C

G

G

A

C

C

A

C

 

AA:

A

T

G

G

T

G

C

G

G

A

C

C

A

C

 

As:

C

C

G

G

T

G

C

A

G

A

C

T

A

C

 

Af:

A

T

G

G

T

T

C

G

A

A

C

C

A

C

 

Mutation:

16

1

3

1

3

1

1

16

7

2

3

16

2

2

 

Ep-350T

16

               

Ep-350T

2

             

T

 

Ep

2

    

C

     

T

 

C

  

Ep

1

     

C

         

Ep

1

               

Ep

1

               

Ep

1

    

C

          

E-T7711G

15

               

E-T7711G

1

               

E-T7447C

27

               

E-T7447C

7

        

A

      

E-T7447C

3

  

A

            

E-T7447C

1

   

A

           

E-T7447C

1

          

T

    

As

9

C

      

A

   

T

   

As

2

C

      

A

 

G

 

T

   

As

2

C

      

A

   

T

   

As

1

C

     

T

A

   

T

   

As

1

C

C

     

A

   

T

   

As

1

C

      

A

   

T

   
  1. Bolditalic are the most common mutation sites
  2. Ep European prototype, AA Asian American lineage, As Asia lineage, Af African lineage
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Cancer Cell International

ISSN: 1475-2867

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