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Fig. 2 | Cancer Cell International

Fig. 2

From: TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling

Fig. 2

Knockdown of TRIM52 suppresses cell proliferation of CRC cells. a Protein expression of TRIM52 in HIEC cell line and 5 CRC cell lines. GAPDH was served as the loading control. b SW480 and LoVo cells were transduced with with lentivirus expressing shRNAs against TRIM52 (RNAi#1, #2, #3 or #4) or with control shRNA (NC) for 48 h. TRIM52 protein expression was analyzed by immunoblot assay. Cells without any treatment were served as negative control. c CCK-8 assays were performed to assess cell proliferation of SW480 and LoVo cells transduced with indicated virus for 0, 24, 48 or 72 h. *p < 0.05, **p < 0.01, ***p < 0.001 vs. NC cells

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