Fig. 4

LncRNA-NORAD modulates the TGF-β signaling pathway. a The cells transfected with si-NORAD indicated TGF-β, Smad2 and Runx2 in the MCF-7 cells downregulated by western blot probing. The cells were transfected with si-NORAD or si-nc. b Quantitative comparison of the expression levels of TGF-β, Smad2 and Runx2 in MCF-7 cells. The protein expression levels in the MCF-7 cells transfected with si-nc were normalized to 1. c, d Comparison of the protein expression levels of TGF-β, Smad2 and Runx2 in the MDA-MB-231 cells. Data were mean ± SD derived from three independent experiments. **p < 0.01 vs the control