Fig. 3

Morin treatment enhances fludarabine- or ibrutinib-induced apoptosis in Mec-1 cells. a, b Flow cytometric analysis of the percentages of Annexin V⁺/PI⁻ in Mec-1 cell samples treated with either DMSO or 50 µM morin, in the absence or presence of fludarabine (ranging from 0.35 to 35 µM, a) or ibrutinib (ranging from 0.1 to 10 µM, b) for 24 h. c, d Flow cytometric analysis of the percentages of Annexin V⁺/PI⁻ in Mec-1 cell samples treated with either DMSO or 3.5 µM fludarabine (c) or 0.1 µM ibrutinib (d), in the absence or presence of morin (ranging from 0.5 to 10 µM). Data reported in the histogram on the right represent the mean values ± SD determined from three independent experiments. ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05