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Table 2 Main characteristics of studies on Lin28B and cancer prognosis

From: Prognostic value of Lin28A and Lin28B in various human malignancies: a systematic review and meta-analysis

First author Case nationality Region Age, years Included number Malignant disease Detected sample Analysis method Survival analysis
Hsu, 2015 Chinese Taiwan Asia 53.80mean 140 EOC Tissue IHC OS/PFS
Tu, 2015 USA North America NA 595 CRC Tissue IHC OS
Wang, 2015 China Asia 46.30mean 58 OSCC Tissue IHC OS
Hu, 2014 China Asia 50.00mean 97 GC Tissue IHC OS
Pang, 2014 China Asia 56.90mean 149 Colon cancer Tissue IHC OS/RFS
Cheng, 2013 Chinese Taiwan Asia 60.00mean 96 HCC Blood qRT-PCR RFS
Wu, 2013 China Asia 60.00mean 72 OSCC Tissue IHC OS/DFS
Diskin, 2012 USA North America 1.42median 87 Neuroblastoma Tissue qRT-PCR OS
Hamano, 2012 Japan Asia 65.00mean 137 OC Tissue IHC OS/DFS
King, 2011 USA North America 66.40mean 88 Colon cancer Tissue Microarrays OS/RFS
Lu, 2009 USA North America 57.90mean 211 EOC Tissue qRT-PCR OS/PFS
  1. EOC epithelial ovarian cancer, CRC colorectal cancer, GC gastric cancer, HCC hepatocellular carcinoma, OSCC oral squamous cell carcinoma, OC oesophagus cancer, PFS progression-free survival, OS overall survival, DFS disease-free survival, RFS recurrence-free survival, IHC immunohistochemistry, qRT-PCR quantitative real-time PCR