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Fig. 5 | Cancer Cell International

Fig. 5

From: PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

Fig. 5

Knockdown of PITX2 inhibited proliferation of LUAD in vivo. a The tumor xenografts were excised and representative images were shown. b, c Knockdown of PITX2 suppressed tumor growth and decreased tumor weight in nude mice (n = 6 per group). d Immunohistochemical staining showed that knockdown of PITX2 reduced the expression of WNT3A, CyclinD1 and C-Myc (*p < 0.05, **p < 0.01, ***p < 0.001)

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