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Table 1 Correlation between PITX2 expression and clinical pathological characteristics

From: PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

Characteristics High level of PITX2 expression (n = 128) Low level of PITX2 expression (n = 128) χ2 p-value
Age (years) 0.46 0.498701
 ≤ 60 42 37   
 > 60 86 91   
Sex 0.14 0.706625
 Male 68 71   
 Female 60 57   
Primary tumor 8.74 0.00311*
 T1–T2 100 117   
 T3–T4 28 11   
Lymph node 0.07 0.788778
 N0 88 86   
 N1–N2 40 42   
Metastasis 6.61 0.0367*
 M0 79 98   
 M1 5 3   
 MX 44 27   
TNM stage 6.52 0.010652*
 I–II 91 108   
 III–IV 37 20   
  1. * Significant correlation