PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway

Table 1 Correlation between PITX2 expression and clinical pathological characteristics

Characteristics	High level of PITX2 expression (n = 128)	Low level of PITX2 expression (n = 128)	χ²	p-value
Age (years)			0.46	0.498701
≤ 60	42	37
> 60	86	91
Sex			0.14	0.706625
Male	68	71
Female	60	57
Primary tumor			8.74	0.00311*
T1–T2	100	117
T3–T4	28	11
Lymph node			0.07	0.788778
N0	88	86
N1–N2	40	42
Metastasis			6.61	0.0367*
M0	79	98
M1	5	3
MX	44	27
TNM stage			6.52	0.010652*
I–II	91	108
III–IV	37	20

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