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Fig. 6 | Cancer Cell International

Fig. 6

From: Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN–AKT axis

Fig. 6

PTEN was downregulated in AOM/DSS induced-CRC mouse model. a Macroscopic inspection of the large bowel after each DSS administration. b Representative histological analysis of colon mucosa after each DSS administration staining with Hematoxilyn and Eosine, ×100 amplification. c mir-26a expression through development of CRC-mouse model measured by RT-PCR and was normalized with RNU6. d PTEN mRNA and e protein levels were measured by RT-PCR and Western Blot, were normalized with GAPDH and b-actin respectively, PTEN was detected after each DSS administration. A healthy, non-treated mouse was used as control

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