TY - JOUR AU - Wang, Si-Li AU - Huang, Yun AU - Su, Rui AU - Yu, Yong-Yang PY - 2019 DA - 2019/04/29 TI - Silencing long non-coding RNA HOTAIR exerts anti-oncogenic effect on human acute myeloid leukemia via demethylation of HOXA5 by inhibiting Dnmt3b JO - Cancer Cell International SP - 114 VL - 19 IS - 1 AB - As an aggressive hematological malignancy, acute myeloid leukemia (AML) remains a dismal disease with poor prognosis. Long non-coding RNAs (lncRNAs) have been widely reported to be involved in tumorigenesis of AML. Here, we define an important role of lncRNA HOTAIR in AML in relation to HOXA5 methylation. SN - 1475-2867 UR - https://doi.org/10.1186/s12935-019-0808-z DO - 10.1186/s12935-019-0808-z ID - Wang2019 ER -