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Fig. 5 | Cancer Cell International

Fig. 5

From: SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals

Fig. 5

SCD1 is required for Gefitinib-induced tumor regression in vivo. Human A549 cells were transfected with lentiviral vector of pcDNA3.1-SCD1 or negative control and subcutaneously injected into nude mice. a, b The tumor size and the mean tumor size (mm3) were analyzed. c The expression of Ki-67 was analyzed in tumor tissues. d The expression of SCD1 was analyzed in tumor tissues. The EGFR/PI3K/AKT signaling, and e the EMT phenotype in tumor tissues were also determined by western blotting. *p < 0.05, **p < 0.01, ***p < 0.001, data is presented as mean ± sd

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Cancer Cell International

ISSN: 1475-2867

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