Fig. 5
From: PGC-1β cooperating with FOXA2 inhibits proliferation and migration of breast cancer cells
Downregulation of PGC-1β combined with FOXA2 promote cell apoptosis and suppress xenograft tumor growth. a, b Apoptosis assay was performed by flow cytometry using the Annexin V/PI staining. c Cells from each treatment group were injected subcutaneously into nude mice. The xenograft models were performed to detect the effect of PGC-1β and FOXA2 on breast cancer growth in vivo according to the tumor weight. d The expression of Ki67 were detected by immunohistochemical assay. *P < 0.05, **P < 0.01, ***P < 0.001