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Fig. 5 | Cancer Cell International

Fig. 5

From: MiR-591 functions as tumor suppressor in breast cancer by targeting TCF4 and inhibits Hippo-YAP/TAZ signaling pathway

Fig. 5

TCF4 up-regulation partially relieves miR-591 mediated suppression of cell proliferation and invasion in breast cancer. a TCF4 mRNA expression in MCF-7 cells transfected with pcDNA-vector or pcDNA-TCF4 was measured using qRT-PCR. b Cell proliferation ability was showed in MCF-7 cells in transfected group including pcDNA-vector, pcDNA-TCF4, TCF4 + miR-591 mimic as detected by Cell Counting Kit-8 assay. c, d Cell invasion ability was showed in MCF-7 cells in transfected group including pcDNA-vector, pcDNA-TCF4, TCF4 + miR-591 mimic as detected by transwell assay. All the data are expressed as the mean ± SD. *P < 0.05

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