Skip to main content

Advertisement

Fig. 1 | Cancer Cell International

Fig. 1

From: Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner

Fig. 1

Hypoxia reduced SIRT1 expression and transcription in SW480 and HCT116 cells. a Western blot analyses of SIRT1 expression levels after HCT116 and SW480 cells were exposed to hypoxia. Scanning densitometry of immunoblotting for each panel was measured (right). b Real-time PCR analysis of SIRT1 mRNA levels after HCT116 and SW480 cells were exposed to hypoxia. c Western blot analysis of SIRT1 expression levels after HCT116 and SW480 cells were treated with cobalt chloride (0, 100, 200, 400 μM) for 24 h. Scanning densitometry of immunoblotting for each panel was measured (right). d Real-time PCR analysis of SIRT1 mRNA levels after HCT116 and SW480 cells were treated with cobalt chloride (0, 100, 200, 400 μM) for 24 h. *p < 0.05; **p < 0.01; ***p < 0.001

Back to article page