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Fig. 6 | Cancer Cell International

Fig. 6

From: Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

Fig. 6

Schematic diagram showing effect of Emodin on colon cancer apoptosis and survival. Emodin modulates JAK/STAT, PI3K/AKT and MAPK/ERK pathways regulating the genes responsible for cell growth, differentiation and proliferation. Emodin regulates intrinsic and extrinsic pathways of apoptosis in CoCa cells by modulating caspase activation and localization and expression of Bcl-2 family proteins

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