Fig. 3From: Impaired redox regulation of estrogen metabolizing proteins is important determinant of human breast cancersE2 controls the ER− stem or non stem cell in a paracrine manner, the self renewal of Erα− stem cells and its differentiation into Erα+ cells depends on amphiregulin secreted by Erα+ cells. Presence of ER+ stem cell inhibits proliferation of Erα− stem cellsBack to article page