From: Association of TNFAIP8 gene polymorphisms with endometrial cancer in northern Chinese women
Variables | Cases (%) n = 226 | Controls (%) n = 248 | P a | Crude OR (95% CI) | P | Adjust OR (95% CI) | P b |
---|---|---|---|---|---|---|---|
Genotypes | |||||||
rs11064 | 0.029 | ||||||
AA | 138 (61.1) | 178 (71.8) | |||||
AG | 70 (31.0) | 60 (24.2) | 1.505 (0.998–2.268) | 0.051 | 1.571 (0.972–2.539) | 0.065 | |
GG | 18 (7.9) | 10 (4.0) | 2.322 (1.039–5.190) | 0.040 | 2.582 (1.034–6.445) | 0.042 | |
AG + GG | 88 (38.9) | 70 (28.2) | 1.622 (1.104–2.382) | 0.014 | 1.778 (1.134–2.782) | 0.012 | |
rs1045241 | 0.529 | ||||||
CC | 143 (63.3) | 167 (67.3) | |||||
CT | 71 (31.4) | 72 (29.1) | 1.152 (0.775–1.712) | 0.485 | 1.144 (0.906–2.299) | 0.122 | |
TT | 12 (5.3) | 9 (3.6) | 1.557 (0.638–3.802) | 0.331 | 1.980 (0.699–5.607) | 0.198 | |
CT + TT | 83 (36.7) | 81 (32.7) | 1.197 (0.819–1.748) | 0.353 | 1.501 (0.961–2.344) | 0.074 | |
rs1045242 | 0.197 | ||||||
AA | 144 (63.7) | 177 (71.4) | |||||
AG | 74 (32.7) | 65 (26.2) | 1.399 (0.939–2.086) | 0.099 | 1.568 (0.980–2.507) | 0.061 | |
GG | 8 (3.6) | 6 (2.4) | 1.639 (0.556–4.831) | 0.370 | 2.695 (0.799–9.084) | 0.110 | |
AG + GG | 82 (36.3) | 71 (28.6) | 1.420 (0.965–2.089) | 0.076 | 1.651 (1.049–2.599) | 0.030 | |
Alleles | |||||||
rs11064 | |||||||
A | 346 (76.5) | 416 (83.9) | |||||
G | 106 (23.5) | 80 (16.1) | 0.005 | 1.593 (1.153–2.201) | 0.005 | 1.719 (1.180–2.506) | 0.005 |
rs1045241 | |||||||
C | 357 (79.0) | 406 (81.9) | |||||
T | 95 (21.0) | 90 (18.1) | 0.265 | 1.200 (0.870–1.656) | 0.265 | 1.457 (1.001–2.120) | 0.050 |
rs1045242 | |||||||
A | 362 (80.1) | 419 (84.5) | |||||
G | 90 (19.9) | 77(15.5) | 0.077 | 1.353 (0.968–1.892) | 0.077 | 1.636 (1.107–2.417) | 0.014 |