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Table 3 Univariate and multivariate analyses of OS in 100 patients with GC

From: The ubiquitin ligase CHIP modulates cellular behaviors of gastric cancer cells by regulating TRAF2

Characteristics Univariate analysis Multivariate analysis
  HR (95% CI) p value HR (95% CI) p value
Age (≤ 65 vs. > 65) 1.005 (0.980–1.031) 0.680
Gender (male vs. female) 1.202 (0.741–1.950) 0.456
Tumor diameter (≤ 5 cm vs. > 5 cm) 1.845 (1.146–2.970) 0.012* 1.814 (1.046–3.146) 0.034*
Site of tumor (cardia vs. body vs. antrum vs. unknown) 1.060 (0.832–1.351) 0.638
Histological types 0.980 (0.788–1.218) 0.856
Tumor differentiation (poorly vs. moderately, well) 1.978 (1.235–3.167) 0.005**
T stage (T3 T4 vs. T1 T2) 2.483 (1.072–5.750) 0.034*
N stage (N3 N4 vs. N0 N1) 2.039 (1.238–3.357) 0.005**
M stage (M1 vs. M0) 4.766 (2.291–9.916) 0.000***
TNM stage (III IV vs. I II) 2.205 (1.540–3.159) 0.000***
CHIP expression (high vs. low) 0.497 (0.287–0.862) 0.013*
TRAF2 expression (high vs. low) 2.970 (1.801–4.898) 0.000*** 2.071 (1.087–3.946) 0.022*
  1. p < 0.05, ** p < 0.01, *** p < 0.001