Table 2 List of 85 genes co-expressed with ESM1 and with r ≥ 0.45
From: Identification of ESM1 overexpressed in head and neck squamous cell carcinoma
Gene symbol | Correlation with ESM1 | P value* | Adjusted p value* | Status | P value** | Adjusted p value** |
|---|---|---|---|---|---|---|
ESM1 | 1.00E+00 | 0.00E+00 | 0.00E+00 | Up-regulation | 1.16E−15 | 2.52E−14 |
ANGPT2 | 7.13E−01 | 3.95E−89 | 4.00E−85 | Up-regulation | 1.41E−13 | 1.94E−12 |
COL4A1 | 6.32E−01 | 1.63E−64 | 1.10E−60 | Up-regulation | 1.28E−21 | 1.75E−19 |
COL4A2 | 6.05E−01 | 6.72E−58 | 3.40E−54 | Up-regulation | 7.94E−20 | 5.22E−18 |
SPRY4 | 5.80E−01 | 3.88E−52 | 1.57E−48 | Up-regulation | 3.66E−18 | 1.49E−16 |
LOXL2 | 5.74E−01 | 5.31E−51 | 1.79E−47 | Up-regulation | 2.00E−22 | 4.31E−20 |
APLN | 5.53E−01 | 1.47E−46 | 4.25E−43 | Up-regulation | 1.04E−13 | 1.48E−12 |
COL10A1 | 5.45E−01 | 3.51E−45 | 8.90E−42 | Up-regulation | 1.48E−22 | 3.72E−20 |
ITGA1 | 5.41E−01 | 2.37E−44 | 5.34E−41 | Up-regulation | 9.44E−13 | 1.12E−11 |
ADAM12 | 5.40E−01 | 3.40E−44 | 6.88E−41 | Up-regulation | 3.23E−22 | 6.24E−20 |
NID2 | 5.38E−01 | 9.24E−44 | 1.70E−40 | Up-regulation | 7.21E−15 | 1.31E−13 |
FLT1 | 5.37E−01 | 1.15E−43 | 1.94E−40 | Up-regulation | 2.76E−06 | 9.80E−06 |
MMP11 | 5.35E−01 | 3.88E−43 | 6.05E−40 | Up-regulation | 1.52E−24 | 1.62E−21 |
BMP8A | 5.33E−01 | 6.04E−43 | 8.74E−40 | Up-regulation | 8.76E−24 | 4.93E−21 |
DLL4 | 5.30E−01 | 2.53E−42 | 3.42E−39 | Up-regulation | 5.77E−09 | 3.33E−08 |
CTHRC1 | 5.29E−01 | 4.40E−42 | 5.57E−39 | Up-regulation | 5.26E−19 | 2.76E−17 |
STC2 | 5.24E−01 | 3.76E−41 | 4.49E−38 | Up-regulation | 1.73E−21 | 2.22E−19 |
HAPLN1 | 5.19E−01 | 2.39E−40 | 2.69E−37 | Up-regulation | 1.54E−19 | 9.23E−18 |
COL13A1 | 5.13E−01 | 2.87E−39 | 3.06E−36 | Up-regulation | 6.35E−22 | 9.97E−20 |
SOX11 | 5.11E−01 | 5.37E−39 | 5.44E−36 | Up-regulation | 1.29E−15 | 2.79E−14 |
MMD | 5.10E−01 | 7.91E−39 | 7.63E−36 | Up-regulation | 5.97E−15 | 1.11E−13 |
LEPRE1 | 5.04E−01 | 7.37E−38 | 6.78E−35 | Up-regulation | 2.31E−21 | 2.71E−19 |
COL5A2 | 5.01E−01 | 3.05E−37 | 2.69E−34 | Up-regulation | 3.63E−20 | 2.74E−18 |
ADAMTSL2 | 5.00E−01 | 3.78E−37 | 3.19E−34 | Up-regulation | 1.19E−16 | 3.32E−15 |
LAMA4 | 4.96E−01 | 2.00E−36 | 1.62E−33 | Up-regulation | 3.53E−07 | 1.46E−06 |
CLIC4 | 4.94E−01 | 3.11E−36 | 2.43E−33 | Up-regulation | 7.44E−13 | 9.03E−12 |
P4HA1 | 4.93E−01 | 5.24E−36 | 3.84E−33 | Up-regulation | 1.32E−17 | 4.60E−16 |
EXTL2 | 4.93E−01 | 5.30E−36 | 3.84E−33 | Up-regulation | 2.34E−09 | 1.45E−08 |
GPR4 | 4.93E−01 | 5.69E−36 | 3.95E−33 | Up-regulation | 1.19E−10 | 9.38E−10 |
GJC1 | 4.93E−01 | 5.85E−36 | 3.95E−33 | Up-regulation | 6.71E−22 | 1.05E−19 |
CCDC102B | 4.92E−01 | 9.19E−36 | 6.01E−33 | Up-regulation | 6.92E−08 | 3.28E−07 |
PLOD1 | 4.90E−01 | 1.41E−35 | 8.68E−33 | Up-regulation | 7.59E−19 | 3.80E−17 |
P4HA3 | 4.90E−01 | 1.41E−35 | 8.68E−33 | Up-regulation | 4.71E−15 | 9.05E−14 |
TMEFF1 | 4.89E−01 | 2.22E−35 | 1.29E−32 | Up-regulation | 5.29E−18 | 2.05E−16 |
C12orf23 | 4.89E−01 | 2.43E−35 | 1.37E−32 | Up-regulation | 8.80E−09 | 4.91E−08 |
SC65 | 4.88E−01 | 3.24E−35 | 1.77E−32 | Up-regulation | 1.17E−18 | 5.49E−17 |
IKBIP | 4.88E−01 | 3.88E−35 | 2.07E−32 | Up-regulation | 3.88E−19 | 2.11E−17 |
ZNF697 | 4.86E−01 | 7.28E−35 | 3.78E−32 | Up-regulation | 5.98E−13 | 7.38E−12 |
CERCAM | 4.85E−01 | 8.37E−35 | 4.24E−32 | Up-regulation | 1.69E−14 | 2.81E−13 |
SPARC | 4.85E−01 | 9.04E−35 | 4.47E−32 | Up-regulation | 1.52E−14 | 2.57E−13 |
PXDN | 4.85E−01 | 1.12E−34 | 5.38E−32 | Up-regulation | 2.28E−13 | 3.03E−12 |
ACAN | 4.84E−01 | 1.35E−34 | 6.35E−32 | Up-regulation | 1.53E−12 | 1.75E−11 |
CHN1 | 4.83E−01 | 2.04E−34 | 9.18E−32 | Up-regulation | 1.93E−16 | 5.06E−15 |
IBSP | 4.83E−01 | 2.35E−34 | 1.02E−31 | Up-regulation | 4.11E−20 | 3.01E−18 |
FNDC3B | 4.83E−01 | 2.38E−34 | 1.02E−31 | Up-regulation | 3.99E−14 | 6.13E−13 |
THY1 | 4.82E−01 | 2.76E−34 | 1.16E−31 | Up-regulation | 4.95E−13 | 6.18E−12 |
FKBP10 | 4.81E−01 | 3.59E−34 | 1.48E−31 | Up-regulation | 4.85E−12 | 5.00E−11 |
COL1A1 | 4.80E−01 | 5.38E−34 | 2.18E−31 | Up-regulation | 6.42E−19 | 3.29E−17 |
CD276 | 4.79E−01 | 9.39E−34 | 3.73E−31 | Up-regulation | 5.95E−22 | 9.68E−20 |
HEYL | 4.78E−01 | 1.22E−33 | 4.76E−31 | Up-regulation | 3.39E−11 | 2.95E−10 |
IL11 | 4.78E−01 | 1.37E−33 | 5.25E−31 | Up-regulation | 1.09E−24 | 1.38E−21 |
SERPINH1 | 4.77E−01 | 1.43E−33 | 5.35E−31 | Up-regulation | 1.85E−22 | 4.31E−20 |
GUCY1A2 | 4.77E−01 | 1.58E−33 | 5.80E−31 | Up-regulation | 1.97E−09 | 1.25E−08 |
LAMB1 | 4.77E−01 | 1.88E−33 | 6.81E−31 | Up-regulation | 5.98E−16 | 1.41E−14 |
PDIA5 | 4.75E−01 | 2.87E−33 | 1.00E−30 | Up-regulation | 3.81E−17 | 1.17E−15 |
TTYH3 | 4.75E−01 | 2.94E−33 | 1.01E−30 | Up-regulation | 6.54E−21 | 6.76E−19 |
COL6A1 | 4.75E−01 | 3.49E−33 | 1.18E−30 | Up-regulation | 4.47E−14 | 6.78E−13 |
COL5A1 | 4.74E−01 | 4.53E−33 | 1.50E−30 | Up-regulation | 5.00E−20 | 3.57E−18 |
CALU | 4.74E−01 | 5.09E−33 | 1.66E−30 | Up-regulation | 3.39E−14 | 5.29E−13 |
KDELR3 | 4.74E−01 | 5.45E−33 | 1.75E−30 | Up-regulation | 3.66E−08 | 1.83E−07 |
COL6A3 | 4.71E−01 | 1.34E−32 | 4.18E−30 | Up-regulation | 2.98E−14 | 4.71E−13 |
EPOR | 4.69E−01 | 2.75E−32 | 8.44E−30 | Up-regulation | 2.58E−12 | 2.82E−11 |
COL11A1 | 4.68E−01 | 3.42E−32 | 1.03E−29 | Up-regulation | 1.48E−15 | 3.16E−14 |
ENO2 | 4.67E−01 | 4.78E−32 | 1.42E−29 | Up-regulation | 3.28E−20 | 2.51E−18 |
PPAPDC1A | 4.67E−01 | 5.91E−32 | 1.74E−29 | Up-regulation | 4.50E−20 | 3.24E−18 |
FN1 | 4.67E−01 | 6.12E−32 | 1.77E−29 | Up-regulation | 2.33E−14 | 3.78E−13 |
POSTN | 4.66E−01 | 8.39E−32 | 2.36E−29 | Up-regulation | 2.13E−16 | 5.50E−15 |
ADAMTS12 | 4.65E−01 | 8.94E−32 | 2.48E−29 | Up-regulation | 3.76E−14 | 5.81E−13 |
NOX4 | 4.65E−01 | 1.15E−31 | 3.10E−29 | Up-regulation | 1.49E−14 | 2.52E−13 |
GLT25D1 | 4.64E−01 | 1.30E−31 | 3.46E−29 | Up-regulation | 3.17E−26 | 1.61E−22 |
ADAMTS7 | 4.61E−01 | 3.73E−31 | 9.69E−29 | Up-regulation | 1.64E−17 | 5.55E−16 |
MFAP2 | 4.58E−01 | 9.93E−31 | 2.55E−28 | Up-regulation | 3.26E−22 | 6.24E−20 |
RCN3 | 4.57E−01 | 1.38E−30 | 3.50E−28 | Up-regulation | 6.41E−15 | 1.19E−13 |
TNFAIP6 | 4.57E−01 | 1.57E−30 | 3.89E−28 | Up-regulation | 1.36E−07 | 6.10E−07 |
C5orf13 | 4.56E−01 | 1.77E−30 | 4.26E−28 | Up-regulation | 1.84E−13 | 2.48E−12 |
VEGFA | 4.56E−01 | 1.92E−30 | 4.58E−28 | Up-regulation | 6.16E−09 | 3.54E−08 |
COL3A1 | 4.55E−01 | 2.53E−30 | 5.95E−28 | Up-regulation | 9.35E−16 | 2.07E−14 |
TBXA2R | 4.55E−01 | 2.84E−30 | 6.62E−28 | Up-regulation | 4.57E−09 | 2.68E−08 |
PCDH12 | 4.55E−01 | 3.20E−30 | 7.38E−28 | Up-regulation | 1.34E−08 | 7.24E−08 |
CDR2 | 4.53E−01 | 4.71E−30 | 1.07E−27 | Up-regulation | 1.71E−11 | 1.58E−10 |
PDGFB | 4.53E−01 | 5.51E−30 | 1.23E−27 | Up-regulation | 8.78E−07 | 3.40E−06 |
ITGA5 | 4.52E−01 | 6.49E−30 | 1.41E−27 | Up-regulation | 8.03E−19 | 3.96E−17 |
FOXS1 | 4.51E−01 | 1.06E−29 | 2.28E−27 | Up-regulation | 2.77E−16 | 7.04E−15 |
PPEF1 | 4.50E−01 | 1.31E−29 | 2.77E−27 | Up-regulation | 9.05E−23 | 2.58E−20 |
IGFBP7 | 4.50E−01 | 1.37E−29 | 2.86E−27 | Up-regulation | 3.15E−10 | 2.28E−09 |