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Fig. 2 | Cancer Cell International

Fig. 2

From: Establishment and characterization of a novel childhood acute lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and 17p deletions

Fig. 2

Cytogenetic analysis of primary leukemia cells and HXEX-ALL1 cells. a G-banding karyotype of primary leukemia cells. The karyotype according to ISCN (2013) can be described as 47, XY, +8, del(9)(p22), del(17)(p12). Arrows indicate +8, del(9)(p22) and del(17)(p12). b CMA of HXEX-ALL1 cells. Arrows indicate the gain of the whole chromosome 8, a 38.56-Mb loss of 9p24.3-p13.1 and a 16-Mb loss of 17p13.3-p11 in all cells. c Cells were lysed, and extracts were analyzed by western blotting for p16 ARF, p14 INK4A and Pax5. β-Actin was used as an internal control. Bar graphs show the ratio of protein to β-Actin. Experiments were performed in triplicate

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