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Fig. 7 | Cancer Cell International

Fig. 7

From: Apatinib preferentially inhibits PC9 gefitinib-resistant cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway

Fig. 7

Protein expression by Western blot for selected proteins in p57/cyclin-E2/Rb signaling pathway in PC9GR cells. a Western blot showing reduced expression levels of cyclin E2, CDK2, pRb and increased expression level of p57 in apatinib-treated cells. b–f Statistical analysis of p27, p57, Cyclin E2, CDK2, and p-Rb expression levels. *p < 0.05, **p < 0.01, ***p < 0.001 compared to control group with 0 concentration

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