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Fig. 3 | Cancer Cell International

Fig. 3

From: HOXA11-AS promotes the progression of oral squamous cell carcinoma by targeting the miR-518a-3p/PDK1 axis

Fig. 3

HOXA11-AS directly targets miR-518a-3p in OSCC. a Bioinformatics analysis of Starbase showed the predicted binding site between HOXA11-AS and miR-518a-3p. b The transfection efficiency of miR-518a-3p mimics in SCC-25 cells was determined by qRT-PCR. c WT-HOXA11-AS or MUT-HOXA11-AS was co-transfected into HEK-293T cells with miR-518a-3p mimics or the corresponding negative controls for the detection of luciferase activity. d The expression of miR-518a-3p in OSCC tissues and matched normal tissues was detected by using qRT-PCR. e The expression of miR-518a-3p was detected in the presence of pcDNA3.1-HOXA11-AS or si-HOXA11-AS by using qRT-PCR. f Negative correlation between HOXA11-AS and miR-518a-3p in OSCC tissues. (*P < 0.05, **P < 0.01, ***P < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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