Fig. 2From: The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferationKnockdown of UTX inhibits cell proliferation in HCT116 and SW620 cell lines. a Western blotting analysis of the indicated proteins in control (scrambled) and UTX knockdown (UTX-KD) HCT116 cells or SW620 cells. b CCK8 assays of CTRL and UTX-KD HCT116 cells or SW620 cells were performed. c Colony formation assays of CTRL and UTX-KD HCT116 cells or SW620 cells were performed. d The effects of UTX on cell-cycle arrest were evaluated by flow cytometry in CTRL and UTX-KD HCT116 cells or SW620 cells. All the experiments were performed at least three times. Data are shown as the mean ± SEM. (*p < 0.05, **p < 0.01, ***p < 0.001, Student’s t-test)Back to article page